Bozena Michniak Kohn, Plant stem cells in cosmetics: current trends and future directions

Plant stem cells in cosmetics: current trends and future directions

Plant regeneration at the cellular and tissue level is a unique process. Similar to animals, the stem cells in plants have properties that help stimulate and regenerate plants after injury. The unique properties of plant stem cells have been a recent area of interest and focus both in developing new cosmetics and studying how these extracts/phytohormones will influence animal skin. This special report focuses on the current evidence-based trends in plant stem cell-based cosmetics and sheds light on the challenges that we need to overcome in order to see meaningful changes in human skin using topical cosmetics derived from plant stem cells.

Lay abstract

A new wave of cosmetic ingredients containing plant stem cells and their extracts has made its way into the industry. What role do these ingredients play in affecting the aging skin? Several ancient practices such as Ayurveda have used plants as a mainstay of treatment for thousands of years. Plant stem cells could hold an interesting role if we can harness these benefits in cosmetics to create safe and effective organic topical skin care.

Plants are equipped with a robust mechanism for regeneration of their tissues under stress. Significant efforts have been put into understanding this mechanism in the expanding field of plant biotechnology [1]. In animals, tissue regeneration occurs following a wound stimulus, resulting in the initiation of organ repair. By contrast, the regenerative efforts made by the plants are not only for tissue repair from damage, but also for the development of a new plant [2]. In other words, cutting the branch of a tree also results in a new bud/branch growth. Can we use this unique property in plants for improving tissue regeneration in animals? “Eat an apple a day…But can it keep aging away?” is thus the question. This report focuses on current applications of plant stem cell-based cosmetics and current research into effects of plant stem cells in human skin.

Claims Substantiation - Gender Matters in Skin Care Testing, Dr. Nava Dayan

Gender Matters in Skin Care Testing (Brief) 

Nava Dayan, Dr. Nava Dayan LLC  09.01.17

Gender differences exist and should be acknowledged and considered in nature, in life, in our work practice and in our communication to consumers. Each study design requires customization when considering the product tested, its components, vehicle and other properties. When conducting an in vitro or in vivo study, key considerations related to gender and gender-age criteria should be weighted for safety and efficacy. Females are profoundly affected by hormonal state, therefore their hormonal state should be examined, considered and documented. It is important to understand their cycle in relation to study endpoint time table collection, their age related hormonal status especially during peri-menopause and menopause. In addition, a thorough baseline should be collected from all individuals that include pH, TEWL and others measures that may be relevant to the study objective.

Nava Dayan, Owner, Dr. Nava Dayan LLC 

Nava Dayan Ph.D. is the owner of Dr. Nava Dayan L.L.C, a skin science and research consultancy and serving the pharmaceutical, cosmetic, and personal care industries. She has 25 years of experience in the skin care segment, and more than 150 publication credits.

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